Myasthenia gravis masquerading as amyotrophic lateral sclerosis: a case report

Myasthenia gravis is an autoimmune disease that causes weakness in the skeletal muscles. It considered to be a relatively rare disease. Most commonly first symptoms are associated with ocular muscle resulting ptosis and/or diplopia may progressive during periods of exertion and resolve rest. However, any group affected leading variability clinical potential challenges diagnostics. We present case report 62-year-old male initially presented bulbar unintentional weight loss, atypical findings electromyography study (the absence decrement amplification combination spontaneous muscular activity) – suggestive for amyotrophic lateral sclerosis (ALS) diagnosis. After thorough investigation diagnosis ALS was not confirmed but myasthenia highly suspected anti-MuSK antibodies came positive. The patient prescribed Pyridostigmine, Prednisolone underwent plasmapheresis procedure which led significant relief symptoms.